BDBM280938 (S)-3-(2-{4-amino- 2-[6-chloro-1-((3- fluoro-4-methyl- pyridin-2-yl) methyl)-1H- indazol-3-yl]-5- methyl-6-oxo- 6,7-dihydro-5H- pyrrolo[2,3-d] pyrimidin-5-yl} 1,3-thiazol-4-yl)- 2,2-dimethyl- propanoic acid::US10030027, Example 216A::US10428076, Example 216A
SMILES Cc1ccnc(Cn2nc(-c3nc4NC(=O)[C@@](C)(c5nc(CC(C)(C)C(O)=O)cs5)c4c(N)n3)c3ccc(Cl)cc23)c1F
InChI Key InChIKey=NOTMCRJEAJHCNC-LJAQVGFWSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 280938
Affinity DataKi: 0.110nMpH: 7.4Assay Description:The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...More data for this Ligand-Target Pair